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An organ-on-a-chip (OOC) in vitro device such as a microfluidic chip with microfluidic flow channels populated by living cells provides an accurate non-animal based high-throughput alternative to traditional lab animal tests. PimBio organ-on-a-chip device allows a user to perform cell-based assays under in vivo like 3D conditions and is especially suited to the in vitro simulation of physiological cellular microenvironment involving interstitial flow biomechanical stimulation. Our organ-on-a-chip platform with standard microscope slide dimensions is a gravity driven microfluidic system compatible with any laboratory pumping system.

PimBio B.V. is focused on development and manufacturing of microfluidic devices for bioengineering physiologically relevant in vitro models for different applications. PimBio supports the 3Rs, the guiding principles of reduction, refinement and replacement of animal experiments.

Applications:

• Provide an accurate non-animal based high-throughput alternative to traditional lab animal tests
• Test the effects of new drug candidates for safety and efficacy in human tissues
• Help scientists elucidate how tissues respond to new drug candidates
• Develop vaccines and drugs to counter bioterrorism threats
• Test the safety and efficacy of cosmetics, chemicals, food ingredients etc.
• Ensure better regulatory decision-making


PimBio organ-on-a-chip microfluidic chip device

About PimBio


PimBio is focused on development and manufacturing of microfluidic devices for bioengineering physiologically relevant in vitro models for different applications. PimBio supports the 3Rs, the guiding principles of reduction, refinement and replacemen of animal experiments … Read more

Products


More physiologically relevant screening devices are needed for drug screening because traditional in vitro models and lab animals are poor predictors of in vivo situation of human body. Organ-on-a-chip (OOC) technology is one of the fastest growing research area in the life science and pharmaceutical … Read more

Collaboration


PimBio works with academic and industry partners to collaboratively develop devices and in vitro models which have unique applications for disease modelling, testing, drug discovery and development. A collaborative relationship allows an exchange of expertise which benefits all parties and ultimately will have positive impacts on human health … Read more

Multimedia


pimbio microfluidic chip devices organ-on-chip

News


Biomedical Materials

PimBio has started to working together with Axxicon Moulds Eindhoven on the organ-on-a-chip application field and feels that we can combine our competences with engineering expertise of Axxicon to be proactive in this challenging new application field and work together towards serving our customers.

New SIA RAAK-PRO funding for in vitro gut models

The Laboratory of the Innovative Testing Research Group of HU University of Applied Sciences Utrecht (The Netherlands) in collaboration with partners has obtained SIA RAAK-PRO funding for development, optimization and implementation of two innovative intestinal in vitro models for evaluation of the safety and efficacy of food ingredients. PimBio B.V. has developed a microfluidic device … Read more

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Mimetas with the next generation of an OrganoPlate! Super!

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