An organ-on-a-chip (OOC) in vitro device such as a microfluidic chip with microfluidic flow channels populated by living cells provides an accurate non-animal based high-throughput alternative to traditional lab animal tests. PimBio organ-on-a-chip device allows a user to perform cell-based assays under in vivo like 3D conditions and is especially suited to the in vitro simulation of physiological cellular microenvironment involving interstitial flow biomechanical stimulation. Our organ-on-a-chip platform with standard microscope slide dimensions is a gravity driven microfluidic system compatible with any laboratory pumping system.
PimBio B.V. is focused on development and small series manufacturing microfluidic devices for bioengineering physiologically relevant in vitro models for different applications. PimBio supports the 3Rs, the guiding principles of reduction, refinement and replacement of animal experiments.
• Provide an accurate non-animal based high-throughput alternative to traditional lab animal tests
• Test the effects of new drug candidates for safety and efficacy in human tissues
• Help scientists elucidate how tissues respond to new drug candidates
• Develop vaccines and drugs to counter bioterrorism threats
• Test the safety and efficacy of cosmetics, chemicals, food ingredients etc.
• Ensure better regulatory decision-making
PimBio is focused on development and manufacturing of microfluidic devices for bioengineering physiologically relevant in vitro models for different applications. PimBio supports the 3Rs, the guiding principles of reduction, refinement and replacement of animal experiments … Read more
More physiologically relevant screening devices are needed for drug screening because traditional in vitro models and lab animals are poor predictors of in vivo situation of human body. Organ-on-a-chip (OOC) technology is one of the fastest growing research area in the life science and pharmaceutical … Read more
PimBio works with academic and industry partners to collaboratively develop devices and in vitro models which have unique applications for disease modelling, testing, drug discovery and development. A collaborative relationship allows an exchange of expertise which benefits all parties and ultimately will have positive impacts on human health … Read more
PimBio has received financial support from the Dutch Ministry of Economic Affairs and Climate under the program “De Subsidieregeling MKB Innovatiestimulering Topsectoren Zuid-Nederland 2015”. The project covers feasibility study for additive manufacturing microfluidica for cell culture designated with the acronym ‘ADAM’. Goal of the project is to obtain insight in the technological feasibility to prototype … Read more
PimBio has received MIT Zuid funding for innovative SMEs. The aim of the project is to evaluate feasibility of developing a novel ‘Microfluidic microtissue in vitro culture’ platform designated with the acronym ‘MUSIC’.
PimBio partner in €3.16M EU Interreg project TTD Cardiovascular diseases come with major personal and societal implications. Within the Interreg Flanders- The Netherlands project Trans Tech Diagnostics (TTD) this public-private consortium of Maastricht University (CARIM, lead partner), University Hasselt (BIOMED), VITO and TSG Innoteq focuses on the development of innovative diagnostic alternatives that allow for … Read more