PimBio works with academic and industry partners to collaboratively develop devices and in vitro models which have unique applications for disease modelling, testing, drug discovery and development. A collaborative relationship allows an exchange of expertise which benefits all parties and ultimately will have positive impacts on human health.
PimBio partner in €3.16M EU Interreg project TTD
Cardiovascular diseases come with major personal and societal implications. Within the Interreg Flanders- The Netherlands project Trans Tech Diagnostics (TTD) this Interreg public-private consortium of Maastricht University (CARIM, lead partner), University Hasselt (BIOMED), VITO and TSG Innoteq focuses on the development of innovative diagnostic alternatives that allow for better assessment of risks to develop cardiovascular diseases.
Main goal of our TTD research and development project is creating innovative options for better cardiovascular diagnostics, increasing the individual quality of life, especially for elderly. Furthermore, TTD provides an open innovation network for public-private collaboration to create the cardiovascular health solutions for the future. PimBio has been invited by TTD consortium to participate in ‘SME industrial research’ of TTD subproject WP4D1: Support of the industrial research of TTD and / or realization of the intended demonstrator. On the basis of the complementarity in expertise, technological objectives and options for (more) future cooperation, PimBio provides good opportunities for cooperation in which all partners can benefit from the cooperation.
Trans Tech Diagnostics is an Interreg V project of the border region Flanders – the Netherlands and receives financial support as part of the European Regional Development Fund (ERDF, €1,580,000), regional governments and TTD partners (€1,580,000; total project budget €3,160,000).
€10K Value Voucher for PimBio
PimBio is developing a unique microfluidic technology to improve both research and diagnostics in cancer. The organ-on-a-chip technology that is used is not yet available as a user-friendly plug-and-play system. PimBio is now developing a system with microfluidic chips, based on concrete market demand.
In order to take the next steps in the development of this technology, PimBio collaborates with CytoSmart to validate the system in an operational (lab) environment. This process has been successfully completed, opening doors to new sources of finance and to (inter) national success. Value Voucher €10K from Value Centre made the collaboration between PimBio and CytoSmart possible.
The consortium is made up of two Universities of Applied Sciences (Hogeschool Utrecht and Fontys Hogescholen), The Hubrecht Organoid Technology foundation, Utrecht University, Wageningen University Research Centre, TNO, the public-private partnership Immuno Valley and other partners for the development and implementation of two innovative intestinal in vitro models incl. ‘gut-on-a-chip’ model. These models, that are derived from fundamental research can play an important role in the safety and efficacy evaluation of food ingredients. The study aims to further develop, optimize and implement the culture models to increase the biological relevance and coincidentally increase applicability of the models, contributing to the adoption of the systems by industry. With the development and especially the implantation of these in vitro models the researchers hope to be able to contribute to the reduction of the use of animals in the safety evaluation of food additives and ingredients. The project is designated with the acronym ‘2REAL-GUTS’.
Microfluidic 3D Cell Culture
Direct visualisation of basolateral cell-to-cell or cell-surface interactions is extremely important for disease modelling, safety evaluation, drug discovery and development. However, in vitro devices designed and produces for direct observation of cellular basolateral interactions are still not available for scientific and industrial community. Therefore there is an urgent need to develop a technology for production of physiologically relevant in vitro devices. PimBio BV and Axxicon Moulds Eindhoven BV collaboratively develop a novel specific technology and know-how for production of microfluidic consumables for in vitro reconstruction and direct visualisation of cellular basolateral interactions.